Study AcronymStudy TitleRegistration NumberPublication
ACLIMAGEEstimating the acute impact of competing mental imagery on craving in alcohol use disorder.NCT04958655Pending
ACTfRACT for RecoveryISRCTN68540929Published
ACTIBAssessing Cognitive behavioural Therapy in Irritable BowelISRCTN44427879Published
ACTMUSAcceptance and Commitment Therapy for Muscle DiseaseNCT02810028Published
ADAPTThe role of anti-IgE (omalizumab) in the management of severe recalcitrant paediatric atopic eczemaISRCTN15090567Published
ADEPTOptimising psychological treatment for Anxiety DisordErs in Pregnancy: a feasibility treatment trialISRCTN81203286Published
ADeSSThe Antidepressant Advisor: A decision support system for UK primary care – a feasibility studyNCT03628027Published
ADVANCEFeasibility of adapting and delivering the ADVANCE technology enabled intervention to reduce intimate partner abuse by men receiving substance use treatmentISRCTN66619273Pending
ADVANCE feasibilityFeasibility and acceptability of a randomised controlled trial of an integrated group intervention to reduce intimate partner violence perpetration among men receiving treatment for substance useISRCTN79435190Published
AerosureCFA short – term comparative study of Aerosure for airway clearance in patients with cystic fibrosisNCT01923753Pending
AerosureCOPDDoes high-frequency airflow oscillation, delivered using Aerosure, increase exercise capacity in severe chronic obstructive pulmonary disease?NCT02007590Pending
AMBITIONMindfulness-based crisis interventions (MBCI) for psychosis within acute inpatient psychiatric settings: a feasibility randomised controlled trialISRCTN37625384Published
APIPPRAArthritis Prevention In the Pre-clinical Phase of RA with Abatacept (APIPPRA)ISRCTN46017566Pending
AneurysmCareAneurysm Care Pilot StudyISRCTN65746249Published
APRICOTTreatment of pustular psoriasis with the IL-1 receptor antagonist anakinra: a randomised, placebo controlled trial and associated mechanistic studies2015-003600-23Pending
ARCThe Addiction Recovery Clinic (ARC): personalised behavioural intervention for opioid use disorderISRCTN69313751Published
ASCOTA phase 3 multi-center double masked randomised controlled trial of adjunctive intraocular and periocular steroid (triamcinolone acetonide) versus standard treatment in eyes undergoing viteroretinal surgery for open globe traumaISRCTN30012492Pending
ASPIAnxiety Symptoms Prevention Investigation (ASPI): Transmission of anxiety from parent to child ? investigating cognitive-behavioural processes, developing and piloting a brief preventative interventionISRCTN57199411Published
ATLANTISAnTiconvuLsant AugmeNtation Trial In Schizophrenia: a randomised, pragmatic double-blind, placebo-controlled trial to assess the effectiveness of valproate augmentation of antipsychotic treatment in patients with residual psychotic symptomsISRCTN77257074Pending
ATOMAtomoxetine for attention deficit hyperactivity disorder (ADHD) in children with special educational needsISRCTN25691213No publication
AVATARReducing the frequency and severity of auditory hallucinations: a randomised clinical trial of a novel Audio-Visual Assisted Therapy Aid for Refractory auditory hallucinations (AVATAR) compared to supportive counsellingISRCTN65314790Published
AWAREPromoting mental health and wellbeing in schools: examining Youth Aware of Mental Health (YAM) and the Mental Health & High School Curriculum Guide (The Guide) in English secondary schoolsISRCTN17631228Pending
BalancingACTBalancing ACT: Evaluating the effectiveness of psychoeducation and Acceptance and Commitment Therapy (ACT) groups for people with bipolar disorderISRCTN73327972Pending
BAP-EFLFeasibility Randomised Controlled Trial of Being a Parent- Enjoying Family Life: a specialised intervention for parents with significant emotional and interpersonal needs.ISRCTN10950727Pending
BARILIFESTYLEEvaluation of the effect of a post-surgery lifestyle intervention compared to usual care upon post-surgery weight loss and changes in body composition, physical activity levels and health-related quality of life in the first year following bariatric surgeryNCT03214471Published
BIORA-PAINComparison of abatacept with tumor necrosis factor inhibitors in the treatment of rheumatoid arthritis pain: A phase IV trial2019-004468-23Pending
BEMINDA comparison to two types of group behaviour therapy for obsessive compulsive disorder: A pilot randomised controlled trial of behaviour therapy and mindfulness-based behaviour therapy for OCDISRCTN52684820Published
BESSTEarly intervention for depression and anxiety in 16–18-year-olds: a multi-centre, cluster randomised control trial of a self-referral psychological stress workshop programme in schools (BESST study – Brief Educational workshops in Secondary Schools Trial)ISRCTN90912799Pending
BISCORTDoes a breathlessness intervention service (‘CBIS’) reduce stress significantly more than usual care in breathless patients with advanced non-malignant disease and their carers? A phase II feasibility studyISRCTN70836126Pending
BREATHLESSNESSDevelopment of King’s College Hospital Breathlessness ServiceNCT01165034Published
BreathePlus FeasibilityBreathe Plus: Feasibility trial of a comprehensive geriatric assessment for people with COPD and frailty attending pulmonary rehabilitationISRCTN13051922Pending
BReFCognitive Behavioural Therapy (CBT) for Renal Fatigue (BReF): A feasibility pilot randomised-controlled trial of CBT for the management of fatigue in haemodialysis (HD) patientsISRCTN91238019Published
CACTUSA parallel arm, biomarker driven, phase II feasibility trial to determine the role of circulating tumour DNA in guiding a switch between targeted therapy and immune therapy in patients with advanced cutaneous melanomaNCT03808441Pending
CADMUSMulti-parametric Ultrasound targeted biopsies compared to Multiparametric MRI targeted biopsies in the diagnosis of clinically significant prostate cancerNCT02712684Published
CALLMECare Augmentation by Location-Linked MessagingISRCTN71271888Pending
CANWALKA study to assess the acceptability and feasibility of a walking intervention for people with recurrent or metastatic cancerISRCTN42072606Published
CAREERCAReer management to improve Education, Employment and Retention for people with anxiety and depressionISRCTN17767032Published
CASA-AFCatheter Ablation vs. Thoracoscopic Surgical Ablation in Long-Standing Persistent Atrial FibrillationISRCTN18250790Published
CASISA randomised pragmatic trial comparing the cost effectiveness of supplementing standard care with an intervention for carers (Carers Assessment, Skills and Information Sharing [CASIS]) of people with eating disordersISRCTN06149665Published
CBDVR2The effect of CBD on paranoid cognitions in humansISRCTN11082858Pending
CBM-paCognitive Bias Modification for ParanoiaISRCTN90749868Published
CIAOIIRandomised controlled trial of the short term effects of OROS-methylphenidate on ADHD symptoms and behavioural outcomes in young male prisoners with attention deficit hyperactivity disorderISRCTN16827947Published
CIICClinical Study of Imagery-based Coping for Cocaine Use DisorderNCT03656653Published
CLARITYClinical efficacy of intravitreal aflibercept versus panretinal photocoagulation for best corrected visual acuity in patients with proliferative diabetic retinopathy at 52 weeks (CLARITY): a multicentre, single-blinded, randomised, controlled, phase 2b, non-inferiority trial013-003272-12Published
CLASSICCan ‘self-confidence workshops’ for depression help the implementation of the NICE Guidelines?ISRCTN26634837Published
CLEOPATRAThe clinical efficacy and safety of light-masks at preventing dark adaptation in the treatment of early diabetic macular oedema: A Multicentre Phase III Randomised Controlled Single-Masked Clinical trialISRCTN85596558Published
CLIPPharmacokinetic study of a novel lipid formulation of cannabidiol (CBD)ISRCTN18067579Pending
CODESCOgnitive behavioural therapy vs standardised medical care for adults with Dissociative non-Epileptic Seizures: A multicentre randomised controlled trialISRCTN05681227Published
CONMANContingency management targeting increased completion of hepatitis B (Hep B) vaccination amongst people in treatment for heroin dependenceISRCTN72794493Published
CONVINCEA study to assess the feasibility and patient acceptability of a randomised, crossover design to compare virtual vs conventional chromoendoscopy for the detection of dysplasia in colitis.NCT02543021Published
COPeEFFIP (E-support for Families and Friends of Individuals affected by Psychosis): A randomised controlled trial of a co-produced online intervention for carersISRCTN89563420Pending
COPEThe effect of frailty on survival in patients with COVID-19 (COPE): a multicentre, European, observational cohort studyN/APublished
CORALCOnceal or ReveALNCT01379014Published
CRAVINGPilot Feasibility Study of Cognitive Control in Cocaine DependenceISRCTN16462783Published
CRIBCognitive Remediation in Bipolar disorder: a feasibility studyISRCTN32290525Published
CRIMSONCRIMSON Study: Randomised controlled trial (RCT) of Joint Crisis Plans to reduce compulsory treatment of people with psychosisISRCTN11501328Published
CRISPCritical time intervention for severely mentally ill released prisonersISRCTN98067793Published
CRUNCHDevelopment of a randomized controlled trial to increase cereal fibre intake to reduce insulin resistance in children.ISRCTN33260236Published
CTAR-SWIFTChin Tuck Against Resistance with Feedback: Swallowing Rehabilitation in Frail Older People – A feasibility studyISRCTN12813363Pending
CUESCoping with Unusual Experiences in Children StudyISRCTN13766770Published
CUESPLUSCoping with Unusual ExperienceS for 12-18 (CUES+)ISRCTN21802136Pending
DAISIESA Randomised Controlled Multi-Centre Open-Label Parallel Group Non-Inferiority Trial of the Clinical Effectiveness, Acceptability and Cost-Effectiveness of a ‘Stepping into Day Treatment’ Approach versus Inpatient Treatment as Usual for Anorexia Nervosa in Adult Specialist Eating Disorder Services (DAISIES Trial)ISRCTN10166784Pending
DATESDiabetes And Telecommunications Study to support self-management for people with type 2 diabetes: a randomized controlled trial(The DATES trial)ISRCTN10342151Pending
DAWNDepression: a trial of antenatal guided self help for womenISRCTN83768230Published
DFENDA randomised, double-blind, placebo-controlled, parallel-group trial of Vitamin D supplementation compared to placebo in people presenting with their First Episode of psychosis Neuroprotection Design (DFEND)2014-002639-32Published
Diabetes StopWatchMotivational Instant Messaging and E-diabetes Prevention Programme for High Risk of Type 2 DiabetesNCT02919397Published
DIMESInsulin intervention development for people with type 2 diabetesISRCTN13339678Published
DISCOVEREarly intervention for depression and anxiety in 16-18 year olds: a feasibility trial of open-access psychological workshops in schoolsISRCTN88636606Published
DISKOThe Effect of Denosumab on Pain and Bone Marrow Lesions in Symptomatic Knee Osteoarthritis: A Randomised Double Blind Placebo Controlled Clinical TrialISRCTN96920058Pending
ECHOExpert Carers Helping OthersISRCTN83003225Published
ECLIPSEECLIPSE Study 9: Building resilience and recovery through enhancing cognition and qualityISRCTN14678860Pending
EFFECT-DEPThe EFFECT-Dep study: Enhancing the effectiveness of electroconvulsive therapy in severe depressionISRCTN23577151Published
EMPIRIKALAn Investigation into the Efficacy of Mirococept (APT070) for Preventing Ischaemia-Reperfusion Injury in the Kidney ALlograft (EMPIRIKAL)ISRCTN49958194Published
EN-PENSA randomised patient-assessor blinded sham controlled trial of External non-invasive peripheral nerve stimulation for chronic neuropathic pain following peripheral nerve injury (EN-PENS trial)ISRCTN53432663Published
EPACSEarly prolonged ambulatory heart monitoring in patients with strokeISRCTN50253271Published
EpAIDImproving outcomes in adults with epilepsy and intellectual disability: a cluster randomised controlled trial of nurse-led epilepsy management (EpAID)ISRCTN96895428Published
EPATHRandomised controlled trial of an app-based digital intervention to support breast cancer survivors prescribed hormone therapyISRCTN51581601Pending
EPIC-HFTExacerbation Prevention in COPD – Effect of Home High-Flow Therapy vs. Usual Care on Hospital Readmission or Death After an Acute Chronic Obstructive Pulmonary Disease (COPD) Exacerbation: a UK-Based Multicentre Randomised Clinical TrialISRCTN89405844Pending
EQUIPPA randomized controlled trial of quetiapine for psychosis in Parkinson’s disease.ISRCTN74681449Published
ERTTPA phase IV, prospective, randomised single-blind UK multicentre, non-inferiority trial of low-dose versus standard dose rituximab for prevention of relapses in acquired TTP2017-001117-86Pending
ESiblingExploratory randomised controlled trial of an online multi-component psychoeducational intervention for siblings of individuals with first episode psychosisISRCTN01416694Published
ESMI MBUThe Effectiveness and cost-effectivenesS of Mother and Baby Units versus general psychiatric Inpatient wards and Crisis Resolution Team services N/APublished
EXPOExtended-Release Pharmacotherapy for Opioid Use Disorder2018-004460-63Pending
EXPRESDA randomised controlled trial to assess the feasibility and efficacy of using an expressive writing intervention with patients on haemodialysisISRCTN19773253Published
FABULASFeasibility study of radiofrequency endoscopic ablation, with ultrasound guidance, as a non-surgical, adrenal sparing treatment for aldosterone-producing adenomasISRCTN86062633Pending
FERAROA prospective, randomised placebo controlled feasibility trial of Faecal microbiota Transplant to ERadicate gastrointestinal carriage of Antibiotic Resistant OrganismsISRCTN34467677Pending
FEVERInfluenza vaccine in nursing homes – why doesn’t it work?ISRCTN28553709Published
FINCHFInCH Study: A randomised feasibility study comparing fluoride interventions to prevent dental decay in older people in care homes.2017-002248-34Pending
FORSUSComparison of the effectiveness of the Twin Block and FORSUS functional appliance for the treatment of Class II division 1 malocclusion patientsISRCTN80447398No publication
FRAMEFITFrame Fit. A randomised controlled trial to determine the acceptability, safety and efficacy of a falls prevention exercise programme for walking frame users.ISRCTN57645734Pending
GETSETGraded Exercise Therapy guided SElf-help Treatment (GETSET) for patients with chronic fatigue syndrome/myalgic encephalomyelitis: a randomised controlled trial in secondary careISRCTN22975026Published
GLIDEGastric Band and Liraglutide Intervention in Diabetes Evolution – A Randomised Double-Blind Placebo-Controlled TrialISRCTN10551314Pending
GOALSA Randomised Controlled Trial of a Brief CBT Intervention to Promote Recovery in PsychosisISRCTN73188383Published
GOLEVELStudy of the Golimumab Exposure-Response Relationship using Serum Trough LevelsNCT03124121Published
GOMARKInvestigating Glutamate and Opioid Mechanisms of Antidepressant Response to KetamineNCT04977674Pending
HFPRCTHelping Families: Psychoeducational Intervention for Parents with Personality DisordersISRCTN14573230Published
HIIT in SMI“Is the use of high intensity interval training (HIIT) feasible and acceptable amongst inpatients with Severe Mental Illness (SMI)?” A Pilot Study.NCT03959735Pending
HINTCan exercise reduce disability in peripheral neuropathy?ISRCTN13311697Pending
HMBICUA study to investigate the effect of β-hydroxy-β-methylbutyrate (HMB) on skeletal muscle wasting in early critical illnessNCT03464708Pending
HOTKIDThe Hypertension Optimal Treatment in Children with Chronic Kidney Disease study: the HOT-KID study – a randomised trial to compare effects of aggressive versus standard targets in blood pressure on target organ damage in children with CKDISRCTN25006406Published
HSENA double-blind, placebo-controlled trial of methylphenidate in children with hyperkinetic disorder and moderate-severe learning disabilitiesISRCTN68384912Published
HTA-SADDHTA Study of Antidepressants for Depression in Dementia: A definitive multi-centre pragmatic randomised controlled double-blind trial of the clinical and cost effectiveness of mirtazapine and sertraline versus placebo for the treatment of depression in dementia presenting in secondary careISRCTN88882979Published
I AM HEALTHAutism spectrum treatment and resilience (ASTAR)ISRCTN91411078Published
IMAGINEA brief early intervention for adolescent depression that targets emotional memories: a feasibility randomised controlled trialISRCTN85369879Published
iMarkHDiMarkHD: Longitudinal Adaptive Study of Molecular Pathology and Neuronal Networks in Huntington’s Disease Gene Expansion Carriers (HDGECs) and Healthy Controls using Positron Emission Tomography (PET) and Multi-modal Magnetic Resonance Imaging (MRI)N/APending
IMPACTImproving physical health and reducing substance use in psychosisISRCTN58667926Published
IMPROVECAREA study to assess the acceptability and feasibility of a walking intervention for people with recurrent or metastatic cancerISRCTN36040085Published
INCVDImaging cerebral neuroinflammation in acute and chronic cerebrovascular disease: a predictor of outcome and biomarker for guiding treatment (IN-CVD)ISRCTN13797354No publication
INSPIREPromoting mental wellbeing in schools using mindfulness, relaxation and strategies for safety and wellbeingISRCTN16386254Pending
InterMuscleA Phase 2 Pilot Physiological Randomised Clinical Trial to Investigate the Effect of Intermittent versus Continuous Enteral Nutrition on Muscle Wasting in Critical IllnessNCT02358512Published
INTERSTAARSAttention Control Training for Infants at Risk for ADHDISRCTN37683928Pending
INVESTINVEST: A feasibility study of psychologically informed vestibular rehabilitation for chronic dizzinessISRCTN10420559Published
IPS-ADEffectiveness and cost-effectiveness of employment support during treatment for drug and alcohol dependence: the Individual Placement and Support for Alcohol and Drug dependence (IPS-AD) trialISRCTN24159790Pending
IPTG01An antimicrobial cream for the treatment of impetigo2008-000036-41Published
IRISInflammatory Response In Schizophrenia (IRIS)NCT03093064Pending
Iron & MuscleMulticentre prospective double-blind randomised controlled trial of the effect of intravenous iron supplementation with or without exercise training in iron-deficient, but not anaemic, patients with chronic kidney disease on exercise capacity, physical function, fatigue and skeletal muscle metabolism.2018-000844-25Published
IRTCShort-term integrated rehabilitation for people with thoracic cancer: A feasibility trialISRCTN92666109Published
JOSHUAJOSHUA: a pilot randomised controlled trial of joint crisis plans for people who self harmISRCTN12440268Published
LASTEffect of Lixisenatide on arterial stiffness in patients with diabetic nephropathy2016-001758-17Pending
LEAVOA Multicentre Phase III Double-masked Randomised Controlled Non-Inferiority Trial comparing the clinical and cost effectiveness of intravitreal therapy with ranibizumab (Lucentis) vs aflibercept (Eylea) vs bevacizumab (Avastin) for Macular Oedema due to Central Retinal Vein Occlusion (CRVO)ISRCTN13623634Published
LIBALipid Ibuprofen versus standard of care for acute hypoxemic respiratory failure due to COVID-19: A multicentre, open label Randomised Controlled Trial2020-001203-16Pending
LICALSLithium Carbonate for patients with Amyotrophic Lateral SclerosisISRCTN83178718Published
LIPSLow dose intravenous immunoglobulin treatment for complex regional pain syndrome2012-000058-73Published
LITELow dose interleukin-2 selectively expands circulating regulatory T cells but fails to promote liver allograft tolerance in humansNCT02949492Published
LivDemA Pilot Randomised Controlled trial to compare changes in quality of life for participants with early diagnosis dementia who attend a “Living well with dementia” group compared to waiting-list controlISRCTN25079950Published
LoTO CASA-AFLong Term Outcomes in Long Standing Persistent Atrial Fibrillation Comparing Catheter Ablation & Thoracoscopic Surgical AblationNCT04280042Pending
LQDLithium versus quetiapine in treatment resistant depressionISRCTN16387615Pending
M4VMindfulness for VoicesISRCTN74054823Published
MAAFAOmega-3 fatty acids supplementation for adolescent boys with attention deficit hyperactivity disorder: a double-blind, randomized controlled trialISRCTN27741572Published
MAGSTARMAGnetic versus STAndard technique for sentinel node biopsy in breast cancer compared in a Randomised controlled trialISRCTN20200149No publication
MARQUEThe MARQUE project: Managing agitation and raising quality of life to improve agitation for people with dementia in care homesISRCTN96745365Published
MelaTools-SSM TrialMelaTools skin self-monitoring study for primary care patients at higher risk of melanomaISRCTN16061621Published
MENOSA trial of a non-medical treatment for menopausal symptoms in women with breast cancerISRCTN13771934Published
MIFCOGCortisol and memory in alcoholics: Mifepristone StudyISRCTN54001953Published
MIMSPilot evaluation of distance delivered mindfulness based cognitive therapy for people affected by primary and secondary progressive multiple sclerosisISRCTN93263909Published
MINDEPUnderstanding the molecular basis for the use of adjunctive anti-inflammatory treatment in treatment resistant depression: a stratified, randomised, placebo-controlled, experimental medicine study using minocycline2015-003413-26Published
MISTERMInimal versus SpecialisT Equipment in the delivery of pulmonary Rehabilitation (MISTER): a randomised controlled trialISRCTN16196765Pending
MINDFULNESS FOR PARANOIAGroup mindfulness-based therapy for distressing persecutory delusions: A pilot study for a randomised controlled trialISRCTN17852603Published
MOLTOSingle arm feasibility of multi-maintenance olaparib after disease recurrence in participants with platinum sensitive BRCAm high grade serous ovarian cancerNCT02855697Pending
MOSAICA Maudsley outpatient study of treatments for anorexia nervosa and related conditionsISRCTN67720902Published
MOSAICA brief physiotherapist-led behaviour-change intervention to facilitate walking in older people with peripheral arterial disease: A randomised controlled trialISRCTN14501418Published
MOVEITA multi-centre randomised controlled trial comparing the effectiveness of enhanced motivational interviewing with usual care for reducing cardiovascular riskISRCTN84864870Published
MRINFORMMR Perfusion Imaging to Guide Management of Patients With Stable Coronary Artery DiseaseNCT01236807Published
MUST-IPFMUscle STimulation in advanced Idiopathic Pulmonary Fibrosis: a randomised placebo-controlled feasibility trial (MUST-IPF)NCT03499275Published
MYPS1Mycophenolate Treatment for Longstanding Complex Regional Pain Syndrome (MYPS I)2015-000263-14Published
N/ALearning from COVID-19 related trial adaptations to inform efficient trial design-a sequential mixed methods studyN/APublished
NACEffect of N-acetylcysteine on Brain Glutamate (NAC)NCT02483130Published
NEATNaltrexone Enhanced Addiction Treatment (NEAT): A randomised controlled trial of the clinical and cost-effectiveness of extended-release naltrexone and oral naltrexone2013-002584-25Published
NEROA randomised controlled trial of non-invasive ventilation (NIV) and hybrid inpatient-home based nutritional education and exercise rehabilitation programme versus NIV alone to reduce weight and increase physical activity in patients with obesity hypoventilation syndromeNCT01483716Published
NeuroMooDComparing fMRI neurofeedback and neurostimulation treatments in self-blaming emotions in major depressive disorder – a pilot trial.ISRCTN10526888Published
NEWMEDS2Neuroimaging effects of a single dose of modafinil on brain activation in patients with schizophreniaISRCTN66900787Published
NEWMEDS3Neuroimaging the effects of modafinil in healthy volunteersISRCTN36604066Published
NHF AECOPDThe role of nasal high-flow to reduce 30-day hospital readmissions following severe exacerbations of Chronic Obstructive Pulmonary Disease: a mixed-methods feasibility studyISRCTN15949009Pending
NHSCHECKNHS CHECK – Health & Experiences of staff working at NHS Trusts and Nightingale Hospitals2021-001279-18Published
NILVADA European multicenre double-blind placebo controlled phase III trial of nilvadipine in mild to moderate Alzheimer’s disease2012-002764-27Published
NOCThe NOC Study (Nitric Oxide in Cognition)NCT02906553Published
NOSTUDYThe Effect of Nitric Oxide on Spatial Working Memory in Patients With Schizophrenia – Pilot StudyNCT02176044Published
NOURISHEDA Randomized Controlled Trial of Mentalization Based Therapy against Treatment as Usual in patients with both Eating Disorders and Borderline Personality DisorderISRCTN51304415Published
OPENFeasibility Randomized-Controlled Trial of Online Acceptance and Commitment Therapy for Painful Peripheral Neuropathy in People Living with HIV: The OPEN Feasibility StudyNCT03584412Published
OPENOlanzapine for young PEople with aNorexia nervosa (OPEN): an open-label feasibility study to test recruitment, treatment acceptance, adherence, safety, and outcome measures assessment and patients’ experience to prepare for a definitive randomised placebo-controlled trialISRCTN80075010Pending
OPTCARE ELDERLYOptimising palliative care for older people in community settingsISRCTN45837097Published
OPTCARE NEUROEvaluation of the clinical and cost-effectiveness of Short-term Integrated Palliative Care Services (SIPC) to OPTimise CARE for people with advanced long-term Neurological conditionsISRCTN18337380Published
OPTIMAOptimising individualised prescribing with therapeutic drug Monitoring for Antipsychotics (OptIMA) 2: clinical pilot study of antipsychotic drug level monitoringISRCTN71305621Published
OPTYCOnline PTSD Treatment for Young People and CarersISRCTN16876240Pending
OUTSMARTOptimized TacrolimuS and MMF for HLA Antibodies after Renal TransplantationISRCTN46157828Published
OZDRYA multicentre prospective randomised clinical trial comparing fixed dosing versus PRN dosing of intravitreal Ozurdex therapy for refractory diabetic macular oedema2012-003661-17Published
PACEA randomised controlled trial of adaptive pacing, cognitive behaviour therapy, and graded exercise, as supplements to standardised specialist medical care versus standardised specialist medical care alone for patients with the chronic fatigue syndrome/myalgic encephalomyelitis or encephalopathyISRCTN54285094Published
PACEUPRandomised controlled trial of a pedometer-based walking intervention with and without practice nurse support in primary care patients aged 45-74 yearsISRCTN98538934Published
PACTA randomised controlled trial of brief physiotherapy informed by Acceptance and Commitment Therapy for chronic low back pain: the PACT studyISRCTN95392287Published
PASTIParent-Administered Screen Time Intervention (PASTI): A 7-week three arm assessor blinded Feasibility and Pilot Randomised Controlled Trial, compared to Bedtime Box Intervention and No Intervention (1:1:1) in toddlers.ISRCTN58249751Pending
PAVEPaclitaxel assisted balloon Angioplasty of Venous stenosis in haEmodialysis accessISRCTN14284759Published
PAZOFOSA phase Ib and Randomised Phase II Trial of Pazopanib with or without Fosbretabulin in Advanced Recurrent Ovarian cancerNCT02055690Published
PD-MINDParkinson’s Disease with Mild cognitive Impairment treated with Nicotinic agonist DrugNCT04810104No publication
PD-RADA translational study investigating PD-L1 expression after radiotherapy for non-small cell lung cancer (NSCLC)NCT03258788Pending
PETTAn external pilot randomised controlled trial to evaluate the performance of a research protocol to compare the Reconsolidation of Traumatic Memories (RTM) intervention with Trauma-Focussed CBT delivered by charities for the treatment of post-traumatic stress disorder (PTSD) in ex-military veteransISRCTN10314773Pending
PNEAssessing the severity of short-term side-effects to a well-known tabletISRCTN47470030Published
POCD2Post-Operative Cognitive Decline 2NCT01743456Published
PollenLite_VIntradermal allergen immunotherapy in adults with seasonal allergic rhinitisISRCTN78413121Published
POPPIESPhase II B randomised placebo controlled trial of pre-operative Botulinum toxin type A in children with cerebral palsy for post-operative analgesiaNCT01437644Published
POSTPost-Deployment Health Screening of Members of the UK Armed Forces – ‘The Post Study’ISRCTN19965528Published
POST2Post-Deployment Health Screening of Members of the UK Armed Forces – ‘The Post Study’ (Phase 2)ISRCTN19965528Published
POST3Post-Deployment Health Screening of Members of the UK Armed Forces – ‘The Post Study’ (Phase 3)ISRCTN19965528Published
PRAISePositive reinforcement targeting abstinence in substance misuseISRCTN01591254Published
PRedSSA Phase II Randomised Controlled Study of Oral Prednisolone in Early Diffuse Cutaneous Systemic SclerosisISRCTN75313566Pending
PREHEATPREHEAT Trial – local heat preconditioning and wound healingISRCTN15744669Published
PRESERVEHow intensively should we treat blood pressure in established cerebral small vessel disease?ISRCTN37694103Published
PROBIT-FProstaglandin insert (Propess) versus trans-cervical balloon catheter for out-patient labour induction: A randomised controlled trial of feasibility (PROBIT-F)NCT03199820Published
PROFITA prospective randomised placebo controlled feasibility trial of Faecal Microbiota Transplantation in cirrhosisNCT02862249Pending
PROMEXGut feeling: understanding the mechanisms underlying the antidepressant properties of probioticsNCT03893162Published
PROMOTEDietary Protein and Skeletal Muscle in Older Twins – Targeting the Gut Microbiome to Overcome Anabolic Resistance: The PROMOTe StudyNCT04309292Pending
PSALTIEfficacy of a Physiotherapy, Speech and Language Therapy Intervention for patients with chronic cough: a randomised controlled trialISRCTN73039760Published
PSALTIMCEfficacy of a Physiotherapy, Speech and Language Therapy Intervention for patients with chronic cough: a randomised controlled trialISRCTN73039760Published
QOLITIQuality Of LIfe Tool for IBD (QOLITI)NCT02707068Pending
QUESTPRQuadriceps neuromuscular electrical stimulation (NMES) as an adjunct to pulmonary rehabilitation (PR) in patients with COPD and quadriceps weakness – a randomised double-blind placebo-controlled trialISRCTN40579508Pending
RACEFITReducing Acquisition of CMV through antenatal Education: A feasibility study to assess an educational intervention to prevent cytomegalovirus infection in pregnancy RACE-FITNCT03511274Published
RADI-CRTA Prospective Randomised Controlled Trial of Cardiac Resynchronisation Therapy Guided by Invasive dP/dt: Radi-CRT StudyNCT01464502Pending
REACTCIPNREACT-CIPN Study: a feasibility randomised controlled trial with process evaluation of a co-designed intervention for chemotherapy-induced peripheral neuropathyISRCTN10025993Pending
REACH-ASDREACH-ASD Trial: A Randomised Controlled Trial of Psycho-Education and Acceptance & Commitment Therapy for Parents of Children recently diagnosed with ASDISRCTN45412843Pending
REDUCePalliative long-term abdominal drains versus repeated drainage in individuals with untreatable ascites due to advanced cirrhosis: a feasibility randomised controlled trialISRCTN30697116Published
REFOCUSA cluster randomised controlled trial of recovery interventions within community based mental health teamsISRCTN02507940Published
REHAB-EPOErythropoietin to facilitate stroke recovery2011-000123-33No publication
RESTReducing Excess Salivation in clozapine Treatment: hyoscine for the treatment of clozapine induced nocturnal sialorrhoeaISRCTN47146067Published
RESTOREA randomised placebo-controlled trial investigating the effect of bilateral quadriceps neuromuscular electrical stimulation on exercise capacity in patients with severe COPDISRCTN15985261Published
RESTSTreatment for insomnia in IAPT servicesISRCTN17064995Published
RESTUSA randomised feasibility study examining daily sedation holds and nocturnal rest using neurally-adjusted ventilatory assist (NAVA) in patients at high risk of prolonged ventilatory failure during recovery from critical illnessNCT01826890Published
RETILASEEfficacy and safety of retinal rejuvenation using Ellex 2RT laser in age-related maculopathyISRCTN87850962No publication
REZONEDeveloping an app to help young people self-manage when feeling overwhelmed during lessonsISRCTN13425994Published
RIOTTInjectable versus oral opioid maintenance treatment for heroin addicts currently failing to benefit from standard treatment: a three way Randomised Controlled Trial (RCT) of injectable heroin versus injectable methadone versus oral methadone maintenanceISRCTN01338071Published
RMCA Pilot Randomised controlled trial of Methotrexate for Chronic Inflammatory Demyelinating PolyradiculoneuropathyISRCTN73774524Published
RTEANSReal-time fMRI Neurofeedback as a novel neurotherapy for children with ADHDISRCTN14491589Published
SCINSCIN (Skin care intervention in nurses) TrialISRCTN53303171Published
SELF-BREATHEA self-guided, internet-based intervention for patients with chronic breathlessness (SELF-BREATHE): feasibility randomised controlled trialNCT04574050Pending
SHAPED-TFStudy of HAllucinations in Parkinson’s disease, Eye disease, and Dementia- Trial FeasibilityISRCTN14435750Pending
SHESelf-management migraine Headache Education: a pilot trialISRCTN53460881Published
SITADSPilot randomised controlled trial of SITAgliptin for Depressive Symptoms in type 2 diabetes2015-004527-32Published
SLOWMOA randomised controlled trial to evaluate the outcomes and mechanisms of a novel digital reasoning intervention for persecutory delusions.ISRCTN32448671Published
SITESupported discharge service versus in-patient treatment in adolescents admitted with psychiatric emergencies: a randomised controlled trialISRCTN82129964Published
SMILESelf-Management education for adults with poorly controlled epilepsyISRCTN57937389Published
SnuggleDownA clinical trial of the effectiveness of sensory weighted blankets in children with autismISRCTN92655217Published
SOFIAAdapted Solution Focused brief therapy In post-stroke Aphasia (SOFIA trial): a feasibility studyNCT03245060Published
STANDA randomised feasibility trial investigating Sativex® for the treatment of the Agitation & Aggression (A/A) in Alzheimer’s Dementia.2020-001056-17Pending
STARStereoTactic radiotherapy for wet Age-Related macular degeneration (STAR): A randomised, double-masked, sham-controlled, clinical trial comparing low-voltage X-ray irradiation with as needed bevacizumab, to as needed bevacizumab monotherapy.NCT02243878Pending
STRIVEIntravenous immunoglobulin (IVIg) treatment of transverse myelitis in adults and childrenISRCTN12127581Published
STRIVEHFStandard Care Versus Triventricular Pacing in Heart FailureNCT02529410Published
SUNSHINEPsychoeducation in families of children with attention deficit hyperactivity disorder (ADHD) in the United KingdomISRCTN26270684Published
SUPASUPA: Supporting UPtake and Adherence to antiretrovirals Applying the Medical Research Council guidance to evaluate an intervention to support uptake and adherence to antiretroviral therapy for HIVISRCTN35514212Pending
SUPERBAdjustment with aphasia after stroke: Exploring the feasibility of a definitive phase III RCT for SUpporting wellbeing through PEeR Befriending (SUPERB)NCT02947776Published
SWANSupporting women with postnatal weight managementISRCTN39186148Published
SWLSleep, Wake and Light therapy for depressionNCT03405493Published
TESLAhomeRandomised controlled trial of domiciliary transcutaneous electrical stimulation in obstructive sleep apnoeaNCT03160456Pending
THRILSafety and Efficacy Study of Regulatory T Cell Therapy in Liver Transplant PatientsNCT02166177Published
TIARAA sham-controlled randomised feasibility study of repetitive transcranial magnetic stimulation (rTMS) as an adjunct to treatment as usual in adults with severe and enduring anorexia nervosa (SE-AN)ISRCTN14329415Published
TIBNFORCETibia plateau pure and split depression fractures (AO 41-B2 and B3) stabilised with N-Force/iN3 bone cement +/- plate augmentation: A prospective single centre feasibility RCT comparing early (2 weeks) versus delayed (6 weeks) weight bearingISRCTN80008225Pending
TIESTelephone delivered Incentives (verbal praise and small financial incentives) for encouraging individuals receiving methadone treatment to attend their pharmacy to take their medication: testing the feasibility of undertaking a future trialISRCTN58958179Published
TiMMThe role of apixaban, aspirin and enoxaparin as Thromboprophylaxis in patients newly diagnosed with Multiple Myeloma – an open label randomised control clinical trial – TiMM2015-002668-18Published
TITRATEA pragmatic randomised controlled open trial of the effect of intensive management (IM) compared with standard care (SC) on remission rates at 12 months in rheumatoid arthritis patients with intermediate disease activityISRCTN70160382Published
TOHETIA single centre randomised, nonblinded, prospective trial to evaluate the use of MRI as the initial imaging modality in the investigation of patients presenting with suspected scaphoid fractureNCT02801149Published
TONICS feasibilityTrial of Neurostimulation In Conversion Symptoms (TONICS): A Randomised Controlled Trial (RCT) feasibility study of Transcranial Magnetic Stimulation (TMS) for conversion disorder with motor symptomsISRCTN51225587Published
ToTSThe Effect of THCV on THCISRCTN93423464Published
T-PACA prospective, randomised, single-centre feasibility study of combined autologous platelet-rich plasma and concentrated autologous bone marrow in adult patients with a fresh unilateral tibial diaphyseal fracture treated with either fine wire ring fixator device (Ilizarov) or reamed intramedullary nailingNCT03100695Pending
TRESORAThe TRESORA study; a study to investigate T cell immune responses during the earliest stages of rheumatoid arthritis.N/ANo publication
TRIANGLEA multicentre randomised controlled trial to examine whether the addition of a patient and carer skills-sharing intervention improves long-term patient wellbeing following hospital treatment for anorexia nervosa.ISRCTN14644379Pending
UANDIDeveloping the evidence base to improve implementation and uptake of CBTp: A feasibility study adopting service user and clinician perspectives to shape a brief pre-CBTp interactive ‘informed choice’ intervention in the South East and London for patient benefitISRCTN53107879Pending
UMANCA Phase I study of a novel synthetic polymer nerve conduit ‘Polynerve’ in participants with sensory digital nerve injuryNCT02970864Pending
UPBEATCase Management for depression and coronary heart diseaseISRCTN21615909Published
V-POPSEvaluating the impact of preoperative Comprehensive Geriatric Assessment (CGA) to improve postoperative outcomes in older vascular surgical patientsISRCTN23142588Published
VACIRISSPneumococcal Vaccination to accelerate Immune Recovery in Sepsis Survivors: randomized placebo-controlled trial2017-002236-17Pending
VISTFPVertebral artery Ischaemia Stenting TrialISRCTN95212240Published
VitaminKThe Additive effect of Vitamin K Supplementation and Bisphosphonate on Fracture Risk in Post-menopausal OsteoporosisNCT01232647Published
VNeSTFeasibility and Acceptability Evaluation of Virtual Reality Supported Therapy for the Negative Symptoms of PsychosisNCT03995420Published
WELLFOCUSPilot randomised controlled trial of a modified intervention to improve well-being in people with psychosisISRCTN04199273Published
WENDYA cross-sectional study comparing the Whooley questions and Edinburgh postnatal depression scale against a diagnostic assessment in identifying depression in pregnancyN/APublished
WORSHIPIIWomen Offenders Repeat Self-Harm Intervention Pilot IIISRCTN18761534Published